Stoichiometric network analysis as mathematical method for examinations of instability region and oscillatory dynamics
Authors: Čupić Ž., Schmitz G., Kolar Anić Lj.
Keywords: Stoichiometric network analysis (SNA); mathematical modeling; stoichiometric models; nonlinear oscillatory reaction system; instability condition
Abstract:
Reaction systems in chemistry, physical chemistry, and biochemistry, which can be described by true or pseudo-stoichiometric relationships between species, and, therefore, represented with stoichiometric models, are usually very complex. For the analysis of the models of these complex nonlinear reaction systems with more than three variables, which can be in different dynamic states like multistability, oscillatority or chaos, some general mathematical methods such as the Stoichiometric network analysis (SNA) must be used. Although the SNA is a powerful method for systematic examination of complex reaction systems, identification of underlying reaction pathways, and stability analysis of dynamic states, this method is practically unknown among mathematicians. Therefore, a simple application of SNA to one five-dimensional model is given here.
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